HIV/AIDS is known to be an incurable disease, and anyone infected by it does not live for long. However, with the change in the technology and emergence of new methods, there are drugs that can refute the above-mentioned statement. Yes, it is true these drugs are helpful in treating and monitoring HIV infection.
People who daily take ART (antiretroviral therapy) can expect a reduction in the quantity of HIV virus in their bodies. It is up to that much extent, that it won’t be shown by blood tests. As they say, a patient with HIV can spread it to others who are healthy, but now it is not going to happen.
However, if you are infected with HIV, and are taking ART drugs, then there is still the presence of the virus in the group cells also called the HIV reservoir. So if you stop continuing it, then the HIV virus becomes active again. So with that being said, one can understand, that HIV is still incurable.
HIV: What is it, how does it happen, and is there hope in curing it?
Before jumping to the conclusion as to whether it is curable or not, first, we need to know what is HIV, and how does it spread among humans. Well, it all happens when the particular bodily fluids of one person enter the body of his/her partner. A person who is infected with HIV can spread the virus to another person who doesn’t have HIV. Now you will ask how these bodily fluids transfer from one body to another.
Even though there are many myths around HIV, still, the most common factor that led to the spread of HIV/AIDS is when two people engage in carnal session, and there it spreads through seminal fluids, vaginal fluids, anal, breastmilk, and even blood. It is not common in the sexual intercourse between a man and a woman, but can also spread through sex with the same genders (gays and lesbians).
Coming to its treatment or whether HIV can be curable or not, it can be possible depending on the development of any drug that can sweep out the virus and makes you free from taking the daily dose of ART, according to scientists.
Two types of HIV cure
While we are discussing the possibility to cure HIV, then it can be done in 2 ways. First is Treatment-free remission, and another is viral eradication. Talking about the former, it can be treated without the need for ART drugs. But a person needs to be regular in taking it daily in life. There are millions of people who are infected with HIV and are unable to take ART drugs and can go for it.
This treatment is also called a functional cure. Even though Ttreatment-free remission treatments are antibody therapies and therapeutic vaccines. Even though it does not guarantee the prevention of infection, still, it can help you in stimulating the immune system to fight the HIV virus. Coming on to the other treatment for HIV cure is viral eradication. You can also understand it as sterilizing cure.
According to scientists, it is conducted in not single but 2 parts. In the first case, it includes drugs that form the cells in the HIV reservoir multiplying it and putting proteins as an indication to the immune system of the affected HIV patient. In the second case, the drugs would spot the protein indicators and then kill the HIV virus.
Apart from these two techniques, there are other preventive measures to fight the HIV virus. These include HDAC (histone deacetylase) inhibitors, latency securing agents, immunotoxins, and protein kinase activators. All these drugs can also be used together. Gene editing is also a technique that has been experimented with by researchers. They are testing it to bring the possibility of inserting the HIV-protective mutation to one’s genes.
Any achievements in getting success?
So are there any successful breakthroughs or say successful cases? Well, if not in the majority, but yes, there has been a success done on some people already.
Even though it sounds very relaxing that with the above-mentioned treatments, the HIV virus can be eliminated but there lies a big challenge for researchers. And it is detecting the working of the HIV reservoirs. Scientists are putting efforts into finding out measures to destroy the HIV virus completely from the body.
So there is a mixed report on the possibility of killing the HIV virus from the human body. In this blog, we mentioned some of the ways that can bring hope to curing HIV patients. These are ART drugs, Treatment-free remission, viral eradication, HDAC (histone deacetylase) inhibitors, latency securing agents, immunotoxins, and protein kinase activators. However, one can avoid having HIV/AIDS if they avoid getting treated with the same needles and use condoms while having any form of sex. MedSure makes efforts in keeping consumers safe from counterfeiting of drugs.